What Is It?
Eosinophilic (ee-oh-sin-o-fil-ick) Gastro-Intestinal disorders are a complex and chronic group of disorders. Put simply, Eosinophilic disorders occur when eosinophils (a type of white blood cell) are found in above normal amounts in various parts of the Gastro-Intestinal tract. When the body needs to attack an allegen, eg: a allergy triggering food or an airborne allergen, eosinophils respond by moving into the area and releasing toxins, and in usual cases protecting the body.
If the body produces too many of the eosinophils, they can cause chronic inflammation in the affected area. This can lead to damage to varying levels of the tissue in the affected area. All Eosinophilic disorders are chronic waxing and waning diseases. This means that the symptoms and severity can vary on a daily basis.
EGID is diagnosed according to the area of the GI tract affected. It is split into 3 main types:
Eosinophilic Oesophagitis (EOE)
A disease characterised by elevated levels of eosinophils in the oesophagus.
Eosinophilic Gastroenteritis (EG)
A disease characterised by elevated levels of eosinophils in the stomach and/or small intestine.
Eosinophilic Colitis (EC)
A disease characterised by elevated levels of eosinphils in the large intestine (colon).